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diethylene glycol monobutyl ether acetate

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In studies with Salmonella typhimurium TA98, TA100, TA1535, TA1537 and TA1538 and Escherichia coli WP2uvrA, diethylene glycol monobutyl ether acetate did not cause any increase in the incidence of mutation in either the presence or absence of a metabolic activation system at concentrations of up to 5000 µg/plate (OECD 2005). The half‐life was less than 3 minutes. Studies with Salmonella typhimurium and Escherichia coli WP2uvrA yielded no evidence that diethylene glycol monobutyl ether acetate has mutagenic potential. As a result of the inadequate documentation, this study cannot be included in the evaluation. In analogy to diethylene glycol monobutyl ether, a MAK value of 10 ml/m3 has provisionally been established also for diethylene glycol monobutyl ether acetate. It cannot be determined from the description of the study whether butoxy acetic acid was a metabolite or an impurity. “Diethylene glycol monobutyl ether” 2008). A study, that was not available to the OECD in the original but only as a summary, reported slight irritation of rabbit skin after exposure to diethylene glycol monobutyl ether acetate (OECD 2005). The ether being relatively unreactive. It is miscible in water, alcohol, ether, … In vitro studies yielded a mean permeability constant of 1.38×10‐3 cm rat skin per hour for diethylene glycol monobutyl ether acetate. The LD50 after the ingestion of diethylene glycol monobutyl ether acetate was 11 920 mg/kg body weight. CAS: 124-17-4: Molecular Formula: C10H20O4: Molecular Weight (g/mol) 204.266: MDL Number: MFCD00009458: InChI Key: VXQBJTKSVGFQOL-UHFFFAOYSA-N: Synonym: 2-2-butoxyethoxy ethyl acetate,butoxyethoxyethyl acetate,diethylene glycol monobutyl ether acetate,butyl diglycol acetate,butyl carbitol acetate,ektasolve db acetate,2-2-butoxyethoxy ethanol acetate,butyl diethylene glycol acetate … “Diethylene glycol monobutyl ether” 2008). Eastman™ DB Acetate (Diethylene Glycol Monobutyl Ether Acetate) is a high boiling glycol ether ester widely used in printing inks, high-bake enamels, and as a coalescing aid in low pH latex paints. 11 octanol/water partition coefficient. Studies carried out with diethylene glycol monobutyl ether in rats did not lead to substance‐induced findings in the offspring after dermal application of up to 2000 mg/kg body weight and day or oral administration of up to 633 mg/kg body weight and day. The dose of 3912 mg/kg body weight and day caused severe haemoglobinuria. Working off-campus? During the first 8 hours, 59% of the low dose and 42% of the high dose were eliminated with the urine. DIETHYLENE GLYCOL MONOBUTYL ETHER ACETATE; NFPA 704. It is used primarily as a coalescing aid in latex paints and as a … After single oral doses of 200 or 2000 mg/kg body weight, radioactively labelled diethylene glycol monobutyl ether acetate was rapidly absorbed and metabolically degraded via diethylene glycol monobutyl ether (see Figure 1). © 2021 Eastman Chemical Company or its subsidiaries. After the application of 2000 mg/kg body weight, the males and females eliminated 12% and 13% of the radioactivity with the urine and 0.4% and 1.4% with the faeces, respectively. All rights reserved. Studies of the ability of diethylene glycol monobutyl ether acetate to penetrate the skin or its sensitizing potential have not been carried out. 2004). In the high dose group, the calculated dermal penetration rate of diethylene glycol monobutyl ether acetate was 1.58 and 1.28 mg/cm2 and hour in male and female rats, respectively. Disposition studies with 14C‐diethylene glycol butyl ether and 14C‐diethylene glycol butyl ether acetate after dermal application to rats, Delayed and immediate hypersensitivity to carbitols, Metabolic studies with diethylene glycol monobutyl ether acetate (DGBA) in the rat, Consensus report for diethylene glycol butylether, diethylene glycol butylether acetate and diethylene glycol isobutylether, OECD (Organisation of Economic Co‐operation and Development). 1993). The MarketWatch News Department was not involved in the creation of this content. Laboured breathing, reduced activity, increased respiratory rate, anorexia, weakness, tremor and straightened posture were observed in the animals at the high doses (OECD 2005). The odour threshold for diethylene glycol monobutyl ether acetate is <0.1 ml/m3 (Lundberg 1995). Diethylene Glycol Monobutyl Ether Acetate Market is a … There are also no valid data for the repeated uptake of diethylene glycol monobutyl ether acetate in animals. Diethylene glycol monolaurate. Several studies were carried out to investigate the effects of diethylene glycol monobutyl ether on offspring after ingestion and dermal application, but no evidence of prenatal or postnatal toxicity was found up to the highest doses tested: in rats, after the administration of diethylene glycol monobutyl ether with the diet on days 1 to 21 of gestation in doses of up to 633 mg/kg body weight and day with prenatal and postnatal examinations and after 13‐week dermal application of 2000 mg/kg body weight and day; in mice, after the oral administration of up to 2050 mg/kg body weight and day on days 6 to 13 of gestation, and in rabbits after the dermal application of up to 1000 mg/kg body weight and day on days 7 to 18 of gestation and prenatal examination (see 111-15-9: Ethylene glycol monoallyl ether: Allyl cellosolve: 111-45-5: Ethylene glycol monobutyl ether: Butyl cellosolve. Flammable and/or toxic gases are generated by the combination of alcohols with alkali … ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). The LD50 for mice was 6468 mg/kg body weight and for guinea pigs 2340 mg/kg body weight. A wide variety of diethylene glycol monobutyl ether acetate c10h20o4 options are available to you, such as grade … Diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether in vitro and in vivo (OECD 2005). There are no studies available of the toxic effects on reproduction of diethylene glycol monobutyl ether acetate. Eastman Cellulose Esters for Formulated Products. Use the link below to share a full-text version of this article with your friends and colleagues. Flammable and/or toxic … Nor was diethylene glycol monobutyl ether found to have any mutagenic effects in the available studies (see Traces of 2‐butoxy acetic acid were detected. The authors did not explain this conflicting result. diethylene glycol monobutyl ether acetate. Diethylene glycol monoricinoleate. The available studies do not provide any evidence of genotoxicity for diethylene glycol monobutyl ether. Diethylene Glycol Monobutyl Ether Acetate is a important solvent, used for ink, paint and coating industry. 1999. Diethylene glycol monobutyl ether had no effect on the mating index, pregnancy incidence or male and female fertility indices after dermal application of 2000 mg/kg body weight and day for 13 weeks. inquire diethylene glycol monobutyl ether acetate CAS NO : 124-17-4; MF : C 10 H 22 O 5 Appearance Colorless and transparent liquid Water Content≤0.05% Acidity≤0.04% ;2-(2-butoxyethoxy)-Ethanol acetate;2-(2-Butoxyethoxy)ethyl acetate… Eastman™ DB Acetate is especially useful in screen inks and as a retarder solvent in coil coatings. There are no data available for the carcinogenicity of diethylene glycol monobutyl ether acetate. Diethylene glycol monobutyl ether acetate is therefore not suspected of having genotoxic effects. See Butyl Carbitol Acetate. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Diethylene glycol monobutyl ether (DEGBE) is produced by the reaction of ethylene oxide and n-butanol with an alkalic catalyst. It is an ether-ester derivative. There are no studies available specifically for diethylene glycol monobutyl ether acetate. … A MAK value of 10 ml/m3 was established for diethylene glycol monobutyl ether. … A worker who had been exposed to diethylene glycol monobutyl ether acetate and diethylene glycol monobutyl ether and had developed acute dermatitis on his hands, arms, face and neck reacted strongly to undiluted diethylene glycol monobutyl ether acetate in a patch test after 48 and 72 hours. Eastman™ DB Acetate (Diethylene Glycol Monobutyl Ether Acetate) is a high boiling glycol ether ester widely used in printing inks, high-bake enamels, and as a coalescing aid in low pH latex paints. Use Of Diethylene Glycol Monobutyl Ether Acetate. Ethanol, 2‐(2‐butoxyethoxy)‐, acetate [CAS Nr. The penetration of undiluted and diluted diethylene glycol monobutyl ether acetate through the skin can be compared quantitatively with that of diethylene glycol monobutyl ether and other glycol ethers. “Diethylene glycol monobutyl ether” 2008). Diethylene glycol monobutyl ether acetate agent detailed information in Haz-Map database. Up to concentrations of 15 ml/m3, diethylene glycol monobutyl ether acetate, like diethylene glycol monobutyl ether, is therefore probably present as a vapour. There are no studies available of the absorption of diethylene glycol monobutyl ether acetate via inhalation. 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Paint and coating industry to share a full-text version of this article your..., ingestion and … diethylene glycol monobutyl ether acetate segment for diethylene monobutyl! Company or its sensitizing potential have not been designated with an alkalic catalyst ready absorption after inhalation is!

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